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Animal & cell study / 2015

The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance

Lee C, Zeng J, Drew BG, et al.

Study overview

Cell experiments and mouse models linked a mitochondrial-derived peptide to folate-cycle changes, AMPK signaling, and metabolic responses.

Results are specific to the study. This is an editorial summary, not personal treatment advice.

Study limitations

The treatment experiments were preclinical. Changes in mice and cultured cells do not establish safe or effective treatment in humans.

About this summary

This summary uses the cited abstract and bibliographic record. Read the original methods and results for the full context.

Read original study

DOI: 10.1016/j.cmet.2015.02.009

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